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WHO Approves Indian Typhoid Vaccine Typbar-TCV for Global Use

Published on January 06, 2018
A new, highly effective vaccine for typhoid has been approved by the WHO (World Health Organization) for global use.

  • Bharat Biotech’s TCV (Typhoid Conjugate Vaccine) against typhoid fever has received pre-qualification from the WHO.
  • The WHO tag would allow the firm to access global public vaccination programmes and this enables the procurement and supplies of the vaccine to the UNICEF, PAHO (Pan-American Health Organization) and GAVI supported countries.
  • Typbar TCV is the world’s first clinically proven TCV.

Typbar TCV

  • Typhoid Conjugate Vaccines are innovative products that have a long-lasting immunity as compared to the already existing vaccines. Only fewer doses of these vaccines are required and it can be given to infants as well through routine childhood immunization programs. It is clinically proven to be administered to children from 6 months of age to adults and provides a long term protection against typhoid.
  • The Hyderabad based firm Bharat Biotech has spent around Rs 150 crore to develop TCVs over a period of 12 years. All aspects of the product were studied and evaluated in human clinical trials.
  • WHO’s SAGE (Strategic Advisory Group of Experts on Immunization) has recommended the use of TCVs for infants between 6 and 23 months of age and catch up vaccinations for children between 2 and 15 years of age.


  • A type of fever caused by the bacterium Salmonella Typhi (S.Typhi) infects humans due to contaminated food and beverage from sewage and other infected humans. 
  • The symptoms of typhoid include fever, fatigue, headache, abdominal pain and diarrhoea or constipation.
  • Currently, one-third of the global population is at risk of typhoid fever. IHME (International Health Metrics and Evaluation) has estimated that in 2016, there were approximately 12 million cases of typhoid fever resulting in around 130,000 deaths globally.
  • The known antibiotics have developed resistance, leaving little protection for people.

Expected Questions

Name the Indian medicine approved by World Health Organisation for typhoid?
a. Typhbar TCV 
b. Typbar TCV 
c. Typhobar TCV 
d. Typobar TCV 

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